Información adicional
- Num_publicacion 76(9-10)
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Resumen_ingles
Introduction: Interstitial lung diseases are a group of rare diseases related to important morbidity and mortality. Peribronchiolar metaplasia, also known as lambertosis, could be found in some of these illnesses.Clinical case: We present a child with respiratory symptoms and need of oxygen since he was an infant. An interstitial alveolar infiltrate was seen in the computarized tomography. According to the clinic and imaging, the first diagnostic approach was an interstitial lung disease. The first lung biopsy was normal. He initially received treatment with cortico-steroids and bronchodilators during years, with no clear improving. A second lung biopsy was performed in which we found changes compatible with lambertosis. Finally, he started treatment with hidroxychloroquine and currently he has a normal life and rarely needs oxygen at home.Discussion: In our patient, despite the normal result of lung biopsy, the diagnosis of interstitial lung disease was not discarded because of the suggestive symptoms, signs and imaging tests. Lambertosis in adults is related to tobacco and infectious agents, but in children genetics seem to be important. The initial treatment were corticosteroids and then hidroxychloroquine.Conclusions: Although the diagnosis is histopathological, a normal lung biopsy does not discard an interstitial lung dis-ease. There is need of more clinical trials to establish the appropriate treatment for these patients.
- Palabras_clave_ingles Interstitial lung disease Lambertosis Lung biopsy
- Todos_autores P. Carrascosa García, C. Rodríguez Jiménez, S. Vigil Vázquez, J.L. Rodríguez Cimadevilla, A. Salcedo Posadas
- autores listados P. Carrascosa García, C. Rodríguez Jiménez, S. Vigil Vázquez, J.L. Rodríguez Cimadevilla, A. Salcedo Posadas
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Correspondecia
P. Carrascosa García. Hospital General Universitario Gregorio Marañón. O’Donnell, 48-50. 28009 Madrid.
Correo electrónico: paulacarrascosag@gmail.com - Titulo_ingles Diffuse interstitial lung disease related to peribronchiolar metaplasia
- Centros_trabajo Sección de Neumología Pediátrica. Hospital General Universitario Gregorio Marañón. Madrid
- Publicado en Acta Pediatr Esp. 2018; 76(9-10): e148-e151
- copyright ©2018 Ediciones Mayo, S.A.
- Fecha recepcion 8/03/17
- Fecha aceptacion 29/08/17
- Tipo de Artículo Clínico (Microdatos) Case Reports
Publicado en
Notas clínicas
Información adicional
- Num_publicacion 68(3)
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Resumen_ingles
Pulmonary disease is a common complication in immunocompromised patients and in many cases to a large extent determines the patient's evolution. In view of the high morbidity and mortality of pulmonary complications, its early diagnosis and an appropriate therapeutic approach are a true challenge for paediatricians faced with the care of these patients on a daily basis.
In recent decades, the development of new therapeutics for the treatment of oncological disease, the usual practice of organ transplants and the increased survival of many of these patients, mean that paediatricians, independently of their field of action, must know how to approach immunocompromised patients and their complications. We aim for this article to be a useful tool for the appropriate management of respiratory complications in those patients.
- Palabras_clave_ingles Immunosuppression pulmonary infiltrates diagnosis bronchoalveolar lavage lung biopsy
- Todos_autores A. Mora, M.J. Rodríguez, T. Fernández, A. Berroya, J.L. Rodríguez Cimadevilla, A. Salcedo Posadas
- autores listados A. Mora, M.J. Rodríguez, T. Fernández, A. Berroya, J.L. Rodríguez Cimadevilla, A. Salcedo Posadas
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Correspondecia
A. Salcedo Posadas. Hospital Maternoinfantil «Gregorio Marañón». Dr. Castelo, 47. 28009 Madrid.
Correo electrónico: asalcedo.hgugm@salud.madrid.org - Titulo_ingles Pulmonary infiltrates in immunocompromised patients
- Centros_trabajo Unidad de Neumofisiología y Pruebas Funcionales. Hospital Maternoinfantil Universitario «Gregorio Marañón». Madrid
- Publicado en Acta Pediatr Esp. 2010; 68(3): 111-118
- copyright ©2010 Ediciones Mayo, S.A.
- Fecha recepcion 03/06/09
- Fecha aceptacion 22/06/09
Publicado en
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